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Bannayan—Riley—Ruvalcaba syndrome BRRS is a rare overgrowth syndrome and hamartomatous disorder with occurrence of multiple subcutaneous lipomas , macrocephaly and hemangiomas. The disease is inherited in an autosomal dominant manner.



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Recognition and characterization of these patients have contributed to elucidate the genetic basis of CRC. Polyposis Syndromes may be categorized by the predominant histological structure found within the polyps.



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